Inventing new chemical reactions is a long-standing passion of chemists, as reflected in the ever-popular field of reaction methodology. Historically, the environment in which newly crafted transformations would be performed imposed minimal limitations on reaction design; after all, solvents can be screened to find an optimal choice, temperature can be modulated, air and moisture can be excluded, catalysts can be added, competing functional groups can be protected, and byproducts can be siphoned away. Such flexibility permitted the use of diverse reagents and conditions, culminating in a vast compendium of synthetic transformations that has been wielded to produce myriad complex chemical structures. The target-driven synthetic chemist now enjoys an impressive reaction toolkit. But what if the challenge were inverted, wherein the target structure was relatively simple but the environment in which the necessary reactions must proceed was so chemically complex and uncontrollable that no two functional groups could combine reliably and selectively under such conditions? Bioorthogonal chemistry, the topic of this special issue of Accounts of Chemical Research , addresses precisely this challenge, with reaction environments of interest ranging in complexity from aqueous solutions of biomolecules to live animals. Dating back just over a decade, the field was launched alongside the growing realization that the molecular details of biological processes can be most accurately understood by probing biomolecules within their native habitats, that is, in cells, or even better, live organisms.
On the Dating Scene
The ECP is designed as a meeting platform for small and medium enterprises in the chemical industry to build new partnerships. Participants have appreciated its creative atmosphere, the nice working collaborations it enabled, the immense business opportunities for start-ups and investors alike, the networking opportunities, and the innovative character of the event as a whole.
Its success is owed to the way people set up and perform their meetings at the event. Instead of individually making appointments at booths or coffee tables, every participant gets access to any other participant via a registration system and can ask for a one-to-one meeting. If both parties agree, this system automatically assigns a time and a table for a minute talk. Besides the talks, companies have the opportunity to present themselves by giving six-minutes speeches, the pitches.
If you are looking for Did you hear about the new dating site for retired chemists? answer then this is the right place.
If you are organizing a chemistry-related event or you have some news or updates that you would like to share with other EYCN members, please send the information to our Communication Team Leader. We aim to stay in touch with everyone and improve communication and knowledge exchange across Europe. The 3rd ECP Summer Summit is going into its third round and for the first time ever it will be taking place on the Internet making it even easier for you to join.
The Summer Summit includes keynote lectures, workshops, panel discussions and as always: many one-on-one meetings that are scheduled in advance. We are cooperating with the organizers to give away 10 tickets to young chemists in academia PhD or PostDoc so lock in your chance to win by sending your brief CV and a description on why you should be picked per mail before August 28th! Because the European Chemistry Congress in Lisbon had to be cancelled due to Covid19, we decided to move all our planned sessions online for free.
Make sure to register and get valuable insights in a diverse range of topics from career tips to the futture of chemistry.
Substitution and elimination reactions. Substitutions (SN1 and SN2) and Eliminations (E1 and E2) are the four most common mechanisms in organic chemistry.
A good place to start our analogy would be with diatomic molecules. For example, two pairs of friends go bowling and leave later as double dates. How long could we expect these HCl molecules to last compared to HI molecules who met at the same party? Using HCl as an example, the bond dissociation enthalpy is the energy required to break every bond in a mole of gaseous HCl molecules. It takes more energy to separate the atoms in HCl — those must be the high school sweethearts destined to stay together.
But what if the H and Cl atoms suffocate each other? They might like to go back and spend some time with their friends, as H 2 and Cl 2 molecules again, but with such a strong bond, this might not be realistic. That is something the HI molecules are more able to do. Unlike the formation of HCl, the reaction between H 2 and I 2 is reversible, meaning that once the reactants have combined to produce HI, some of the products will go back to H 2 and I 2.
A Decade of Bioorthogonal Chemistry
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience.
The study of chemistry has a long and rich history at William & Mary, with references dating back to Thomas Jefferson. Today the Chemistry Department offers.
I have been interested in both science and history since childhood, and though I ended up specializing in science, I remained fascinated by the past. During the final year of my integrated chemistry degree at Oxford University, I was offered a one-off opportunity to work in an archaeology research lab, studying nitrogen isotopes to learn about the diet of Paleolithic humans.
Within weeks, I knew it was exactly the type of research I wanted to do; being able to use chemistry to understand our past was a dream come true. I went on to a PhD project that focused on amino acid racemization also known as amino acid dating in fossilized shells at Newcastle University. I have been working in amino acid racemization of fossilized materials ever since.
My PhD supervisor, Matthew Collins, had a strong focus on archaeological science, with one set of researchers working predominantly on bone and another on pottery, but I was the only one working on shells and focusing on their potential for dating. After a fantastic three months being trained at Northern Arizona University with Darrell Kaufman, I set up the amino acid lab in Newcastle. Anybody can analyze a fossil but, when it comes to geochemistry, the key issue is: how do we really know if we are looking at the original molecules?
The tricky bit is being able to isolate the part you want to look at, without altering it in the process. The reactions that the protein is subjected to in this intra-crystalline fraction are predictable, making it possible to use these to accurately date the sample. To isolate such preserved proteins, we pre-treat our samples with bleach, to remove contamination and any exposed open system amino acids 1.
We also routinely analyze multiple amino acids — both free amino acids FAA and total hydrolysable amino acids THAA — as these show different levels of protein breakdown that are highly correlated 2. In this way, we can draw conclusions about the age of the sample and the temperatures it has experienced. I soon found that some minerals hold onto this intra-crystalline protein much better than others.
Download your FREE white paper on green analytical chemistry. To celebrate the international year of chemistry, James Mitchell Crow looks back at some of the discoveries and developments made by chemists over the past six decades. Where do we come from? What was life like for our ancestors? Such questions have long played on the mind of humans, and thanks to chemistry – and the action of cosmic rays – we now have a good part of the answer.
Cosmic rays colliding with the top of the atmosphere were found to be generating neutrons, which react with nitrogen to form carbon, ejecting a proton in the process. This produces a steady input of radioactive carbon into the biosphere, which decays with a half-life of about 5, years. Willard Libby received the Nobel prize in chemistry for his pioneering work on carbon dating.
Mobile apps for chemists and chemical engineers
Online services are available. For updates visit library. The Libraries are resuming limited in-person research activities by appointment only as part of the University’s Research Restart Plan. Learn more about the Libraries’ entry requirements and available services. This guide contains tablet and smart phone apps of potential interest for chemists and chemical engineers.
Mobile resources may be available in iOS or Android, or may be web sites that support mobile devices.
Unfortunately, both are rather out-of-date and initially promised regular revisions have not yet appeared. Comprehensive Coordination Chemistry, Eds. G.
How can I make a flexible solar cell out of organic molecules? Can I build a car engine on a molecular level? Can I synthesize life? Can I cure tuberculosis? You will encounter such questions in the Master’s degree program in Chemistry at the University of Groningen. The 2-year program is fully taught in English and embedded in an internationally leading research environment. It is organized along with three main specializations:.
Focus of this specialization lies in the chemistry of functional materials, including aspects like material synthesis and self-assembly, supramolecular chemistry, structural characterization techniques, and functional properties.
European Chemistry Partnering: Industry Speed Dating
The turn of the century was also a turning point in the history of chemistry. Consequently, a survey of the Nobel Prizes in Chemistry during this century will provide an analysis of important trends in the development of this branch of the Natural Sciences, and this is the aim of the present essay. Chemistry has a position in the center of the sciences, bordering onto physics, which provides its theoretical foundation, on one side, and onto biology on the other, living organisms being the most complex of all chemical systems.
Reaxys contains experimental chemical and physical property data and reaction information published in the chemical literature dating back to Most of the.
Search events Submit an event Other information. This biennial conference, dating back to , is dedicated to gather young researchers from all subfields of Chemistry, as well as other related scientific areas of research. Young chemists and researchers from any nationality are particularly encouraged to share their scientific highlights amongst their peers from chemical sciences, expand their international research network, and attend lectures from recognized experts in various field of Chemistry.
Main Topics: Analytical chemistry Biochemistry Chemistry of natural products Computational chemistry Electrochemistry Food chemistry Green chemistry Inorganic chemistry Materials chemistry and nanomaterials Medicinal chemistry Organic chemistry Physical chemistry Polymer chemistry Surface chemistry and interfaces Teaching and disseminating chemistry Other suggestion. Deadlines Mar 01 Oral abstracts deadline. Poster abstract deadline.
Early bird registration deadline.